Lymphopenia-Induced T Cell Proliferation Innate Immune Cell CD45 Regulates
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منابع مشابه
Modulation of immune cell signalling by the leukocyte common tyrosine phosphatase, CD45.
CD45 is a leukocyte specific transmembrane glycoprotein and a receptor-like protein tyrosine phosphatase (PTP). CD45 can be expressed as several alternatively spliced isoforms that differ in the extracellular domain. The isoforms are regulated in a cell type and activation state-dependent manner, yet their function has remained elusive. The Src family kinase members Lck and Lyn are key substrat...
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تاریخ انتشار 2014